Where high-performance DAQ meets
unparalleled ease of use

The Cerebus™ System is a multichannel data acquisition system for animal neurophysiology experiments that is highly configurable and easy to use. The Cerebus™ Neural Signal Processor captures, processes and analyzes action potentials (spikes), field potentials and other physiological signals in relation to experiment state events™ in real-time for up to 256 electrodes, 16 auxiliary analog channels, and individual TTL or strobed word experiment events. Multiple systems can be synchronized for higher channel counts. The Cerebus System also can be used in combination with the innovative CerePlex™ family of digital headstages, which digitize and multiplex neural signals at the source, enabling noise-immune transmission and reduction of lead wires.

Cerebus™ System features and benefits


  • Ultra-compact design

  • Fiber-optic link for noise immunity

  • 8, 16, 32, 64, 96, 128, 256 and 512 channel configurations

  • High-resolution signal recording (30 kHz at 16 bits)

  • Compatible with low- and high-impedance electrodes

  • Electrode impedance measurement

  • Flexible I/O options for synchronizing with behavior, stimulus and video systems

  • Parallel multi-PC control and operation


  • Per-channel user-defined digital filters

  • Up to three signal streams per channel

  • Real-time 2D/3D spike sorting (including tetrodes)

  • Two-channel oscilloscope (time and frequency modes)

  • User-defined analog outputs

  • Digital noise cancellation

  • Crosstalk calculation

  • Interface to NeuroExplorer, Spike2, MATLAB, C/C++ and other third-party software

  • SDKs for MATLAB and C++ (offline and online)

  • Natively integrates with Blackrock’s Offline Spike Sorting (BOSS) software

Compatible products

Cerebus™ System specifications

Neural Signal Processor with Experiment I/O

Digital signal processingAdaptive noise cancellation and 4th-order high/band/low pass digital filtering; Separate digital filters for simultaneous field potential and spike processing for all channels
Experiment analog inputsSixteen ± 5.0 V, 16-bit analog inputs for experiment or neural signals (BNC)
Experiment analog outputsFour ± 5.0 V, 16-bit analog outputs (BNC)
Two line-level audio outputs (BNC + 3.5 mm)
Experiment TTL and strobed-word inputsOne 16-bit input port (DB-37) with individual or strobed-word event detection
Experiment digital outputsFour single-bit digital outputs (BNC), Synchronization TTL output (BNC)
Experiment serial inputRS 232 port (DB-9), 115 kbps
PC interface1 Gbit Ethernet
Power supply3-pin PC power connector
(110-240 VAC, 50-60 Hz)
Dimensions88 mm (H) x 325 mm (W) x 425 mm (L)
Weight6.8 kg
Mounting optionsTable-top rubber feet or 2 U slot in 19-inch instrument rack

Host PC (not included with system)

Recommended System Specifications: Quad Core Intel® i7 or AMD equivalent CPU; 8 GB RAM; 2 TB Hard drive; 250 GB SSD; gigabit Ethernet port; dedicated Graphics card; Windows 7 64 Bit

Instruction Manual

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