Measure OMR with minimal experimenter effort

Optomotor response (OMR) is a reflex used to assess vision in mice. In order to evoke OMR, a mouse watches a rotating cylinder with a striped pattern. Stimulus correlated head movements are quantified to determine visual thresholds. The qOMR (quantitative OMR) is a unique system that automatically measures OMR with minimal experimenter effort. It uses a virtual stimulation sphere that constantly aligns with the animal´s head position. Based on real-time head tracking quantitative OMR measurements run fully automatically and objectively.

Quantitative optomotor response (OMR) features & benefits

Simple, robust, and non-invasive test to examine vision in rodents
Fully automated measurement and analysis: no manual positioning of the stimulus, no specially trained experimenter required, time and cost effective, and unbiased
As a reflex, OMR measurements do not require animal training
Freely behaving animals, no surgery, no fixation
Flexible, user-friendly experimental design and data handling.
Calibrated 4 screen environment for presenting the virtual stimulation sphere
Elevated central platform for placing the unrestrained animal
Top and bottom mirror to create an illusion of infinite depth
IR-camera with adjustable IR-illumination for automated head tracking.

qOMR applications

1. Investigation of various aspects of vision in mice and other rodents

Visual acuity
Contrast sensitivity
Spectral sensitivity
Temporal sensitivity

2. Characterisation or preclinical testing in relevant disease models, for example

Glaucoma
Retinal degeneration
Diabetes
Aging

3. Examination of axonal regeneration

qOMR compatible products

Cerebus™ System

CerePlex™ Direct